Generic Doxycycline (Doxycycline)

Doxycycline is a synthetic, broad-spectrum antibiotic derived from tetracycline. It is used to treat a wide range of bacterial infections, including those of the urinary tract, acne, gonorrhea, chlamydia, and periodontitis (gum disease). It is also effective against blemishes, bumps, and acne-like lesions caused by rosacea.

This medication should be taken after meals with a full glass of water to reduce irritation of the esophagus. The daily dose may be taken all at once or split into two doses 12 hours apart. Do not exceed the prescribed amount or continue the medication longer than recommended. Some brands of doxycycline may not be taken with dairy products, as dairy can interfere with absorption. Delayed-release capsules should not be crushed, broken, or opened—swallow them whole. If using an oral suspension, shake the bottle well and use a proper measuring device. Do not take doxycycline if it is expired, as it may cause kidney damage.

Doxycycline use during the period of tooth development (such as in children under 9 years of age) can result in permanent discoloration of teeth. Infections caused by Staphylococcus, Escherichia coli, and Shigella should only be treated with this medication after sensitivity is confirmed. Patients should avoid excessive exposure to sunlight or tanning beds during treatment and for 4–5 days afterward due to increased sensitivity to UV light. For long-term treatment, regular monitoring of blood cell counts, liver function, and kidney parameters such as urea and nitrogen levels is recommended.

This medication is contraindicated in individuals with known hypersensitivity to doxycycline or other tetracyclines, during the second half of pregnancy, while breastfeeding, in infants and children under 9 years old, and in patients with conditions such as severe liver failure, porphyria, or leucopenia.

Possible side effects of doxycycline may include headache, dizziness, blurred vision, fever, chills, body aches, skin rashes, jaundice (yellowing of the skin or eyes), dark urine, severe upper abdominal pain, loss of appetite, and unusual bruising or bleeding. Notify your healthcare provider immediately if you experience any severe side effects.

Doxycycline’s effectiveness may be reduced when taken with certain antacids that contain aluminum, magnesium, or calcium, as well as mineral supplements (like calcium or iron) or bismuth subsalicylate. It can increase the effectiveness of warfarin (a blood thinner), while drugs such as phenytoin (Dilantin), carbamazepine (Tegretol), and barbiturates (e.g., phenobarbital) may increase the breakdown of doxycycline, lowering its effectiveness.

If you miss a dose, take it as soon as possible unless it is almost time for your next scheduled dose. In that case, skip the missed dose—do not double up.

Overdose symptoms may include persistent nausea, vomiting, or diarrhea. Seek medical attention if an overdose is suspected.

Store doxycycline at room temperature between 59°F and 77°F (15°C to 25°C), away from light, moisture, children, and pets. Never use the medication after its expiration date.

This information is intended for general educational purposes and does not replace professional medical advice. Always follow the specific guidance of your healthcare provider. We disclaim any liability for harm resulting from the use of this information or from attempts at self-treatment.