Generic Glycomet (Metformin)

Common Use
Glycomet is an oral antidiabetic medication used to treat type 2 diabetes in adults. Its active ingredient is Metformin, a member of the biguanide class of drugs. Metformin works by lowering glucose production in the liver, reducing glucose absorption in the gastrointestinal tract, and increasing insulin sensitivity in body tissues. It does not cause hypoglycemia when used alone and may help with weight stabilization or reduction. Glycomet is often prescribed when treatment with sulfonylureas has been ineffective, especially in overweight patients.

Dosage and Administration

• Only take Glycomet if it has been prescribed for you.

• The standard adult dosage is 500 mg twice daily or 850 mg once daily, taken with meals.

• The dosage may be increased based on blood glucose levels up to a maximum of 2550 mg daily, divided into three doses.

• Always follow your doctor’s instructions.

• Take the medication with food to minimize gastrointestinal side effects.

Precautions
Glycomet can, in rare cases, cause a serious condition called lactic acidosis, particularly in those with kidney or liver problems. Seek immediate medical help if you experience:

• Muscle pain, weakness

• Drowsiness or extreme fatigue

• Slow heart rate

• Cold sensation

• Difficulty breathing

• Abdominal pain or fainting

Also be alert for symptoms of low blood sugar (hypoglycemia): hunger, confusion, irritability, tremors, sweating, fast heartbeat, or fainting.
Avoid alcohol, which increases the risk of both lactic acidosis and hypoglycemia.

Contraindications
Do not take Glycomet if you have any of the following:

• Allergic reaction to Metformin

• Type 1 diabetes, diabetic ketoacidosis, or hyperglycemic coma

• Kidney or liver failure

• Heart failure or recent myocardial infarction

• Dehydration, severe infections, or respiratory failure

• Alcoholism

• Severe trauma or surgery

• Age over 60 combined with strenuous physical activity

• Low-calorie diet (<1000 kcal/day)

• Pregnancy or breastfeeding

• Use of iodinated contrast materials for imaging (pause use before/after scans)

Possible Side Effects
Common side effects include:

• Nausea, vomiting

• Diarrhea, bloating, or gas

• Loss of appetite

• Weight gain or swelling

Severe but rare effects include lactic acidosis symptoms (as above) and allergic reactions such as rash, swelling, or hives. Seek emergency help if these occur.

Drug Interactions
Glycomet can interact with multiple drugs.
Increased Glycomet effect:

• Sulfonylureas

• Insulin

• MAO inhibitors

• Acarbose

• Salicylates

• Cyclophosphamide

• Oxytetracycline

• Cimetidine (Tagamet)

Decreased Glycomet effect:

• Thyroid hormones

• Oral contraceptives

• Corticosteroids

• Epinephrine, glucagon

• Thiazide diuretics

• Nicotinic acid derivatives

Avoid alcohol and consult your doctor before combining Glycomet with any other medication.

Missed Dose
If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. In that case, skip the missed dose. Do not double up to make up for a missed dose. Resume your normal dosing schedule.

Overdose
Overdose symptoms are primarily signs of low blood sugar:

• Confusion, tremors

• Hunger, dizziness

• Sweating, fast heartbeat

• Fainting, seizures, or coma

Emergency treatment is required if overdose or symptoms of lactic acidosis occur.

Storage
Store at room temperature (20–25°C or 68–77°F) in a dry, light-protected place.
Keep out of reach of children and do not store in bathrooms.

Disclaimer
This summary is provided for general informational purposes only. It does not cover all directions, drug interactions, or safety warnings. It should not be used for self-diagnosis or treatment. Always consult your healthcare provider for medical advice specific to your condition. We are not responsible for any consequences arising from the use or misuse of this information.