Generic Tricor (Fenofibrate)

Common Use
Tricor contains the active substance fenofibrate, which is converted in the body to fenofibric acid, its active form. It is used alongside dietary modifications to treat individuals with very high triglyceride levels or mixed lipid disorders. Tricor works by increasing lipoprotein lipase activity, promoting the breakdown of very low-density lipoproteins (VLDL), transferring cholesterol to high-density lipoproteins (HDL), and reducing VLDL synthesis. This results in improved lipid profiles and helps manage cardiovascular risk.

Dosage and Direction
Tricor is typically taken orally. For treating high cholesterol or combined high cholesterol and triglycerides, the usual starting dose is 160 mg three times daily. For isolated high triglyceride levels, the initial dose ranges from 54 mg to 160 mg once daily, and may be gradually increased every 4 to 8 weeks based on response, up to a maximum of 160 mg per day. Always follow your physician’s dosing instructions precisely.

Precautions
Patients on Tricor should have their liver enzymes (transaminases) monitored regularly. If levels of ALT are elevated more than twice the normal limit—especially if accompanied by muscle pain or weakness—treatment should be discontinued. Long-term treatment with Tricor should be combined with a hypolipidemic diet and closely supervised by a healthcare provider. Tricor may increase the risk of gallstones.

Contraindications
Tricor is contraindicated in individuals with known hypersensitivity to any of its components. It should also be avoided in patients with severe liver or kidney dysfunction, gallbladder disease, or persistent unexplained liver enzyme elevations.

Possible Side Effects
Reported side effects include gallstones (cholelithiasis), elevated liver enzymes and creatine kinase, nausea, vomiting, diarrhea, muscle pain (myalgia), muscle inflammation (myositis), and in rare cases, rhabdomyolysis, which can lead to acute kidney failure. Other effects may include dizziness, headache, abdominal pain, back pain, fatigue, impotence, and skin rash. If any of these symptoms occur, contact your doctor promptly.

Drug Interactions
Before starting Tricor, inform your doctor of all medications you are taking, including over-the-counter and herbal supplements. Tricor may interact with:

• Blood thinners (e.g., warfarin)

• Cyclosporine

• MAO inhibitors (e.g., selegiline, phenelzine)

• Diabetic medications (e.g., glipizide, insulin)

• Estrogens and oral contraceptives

• Statins (e.g., lovastatin, simvastatin)

• High-dose niacin (≥1 g/day)
  Concomitant use with statins or high-dose niacin increases the risk of myopathy or rhabdomyolysis.

Missed Dose
If a dose is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.

Overdose
Although specific symptoms of Tricor overdose are not well known, taking too much can be dangerous. If an overdose is suspected, seek emergency medical attention immediately.

Storage
Store Tricor at room temperature (59–77°F or 15–25°C), protected from light and moisture. Keep the medication out of reach of children and pets. Do not use after the expiration date.

Disclaimer
This information is provided for general educational purposes and does not replace medical advice from a healthcare professional. It does not cover all possible uses, precautions, interactions, or side effects. Always consult your physician or pharmacist before starting or stopping any medication. We do not accept responsibility for any loss, damage, or consequences resulting from the use or misuse of this information.